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Dabigatran ethyl ester

CAS No. 429658-95-7

Dabigatran ethyl ester( Dabigatran ethyl ester | BIBR-951CL | BIBR 951CL | BIBR951CL | UNII-KJ4EH9410G )

Catalog No. M14458 CAS No. 429658-95-7

A reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dabigatran ethyl ester
  • Note
    Research use only, not for human use.
  • Brief Description
    A reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM.
  • Description
    A reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM; an anticoagulant agent used to prevent stroke with atrial fibrillation.Thrombosis Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Dabigatran ethyl ester | BIBR-951CL | BIBR 951CL | BIBR951CL | UNII-KJ4EH9410G
  • Pathway
    Autophagy
  • Target
    Thrombin
  • Recptor
    Thrombin
  • Research Area
    Cardiovascular Disease
  • Indication
    Thrombosis

Chemical Information

  • CAS Number
    429658-95-7
  • Formula Weight
    499.5643
  • Molecular Formula
    C27H29N7O3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(OCC)CCN(C(C1=CC=C2C(N=C(CNC3=CC=C(C(N)=N)C=C3)N2C)=C1)=O)C4=NC=CC=C4
  • Chemical Name
    β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wienen W, et al. Thromb Haemost. 2007 Jul;98(1):155-62. 2. Kansal AR, et al. Heart. 2012 Apr;98(7):573-8.
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